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Anti-mullerian-hormone



Why Get Tested

In women to evaluate ovarian function and fertility sometimes in the evaluation of polycystic ovarian syndrome PCOS or to evaluate the effectiveness of ovarian cancer treatment in an infant to evaluate the presence of external sex organs that are not clearly male or female ambiguous genitalia and or function of the testicles in an infant boy

When To Get Tested

When a health practitioner wants to evaluate a woman s fertility predict onset of menopause or suspects PCOS sometimes prior to some assisted reproductive procedures periodically when a woman is undergoing treatment for an AMH-producing ovarian cancer when it is suspected that the testicles of an infant boy are absent or not functioning properly

Sample Required

A blood sample drawn from a vein in your arm

Test Preparation Needed

None




Common Questions


Anti-M llerian hormone AMH is not a routinely ordered test but may be useful in specific circumstances AMH is a hormone produced by reproductive tissues Its role and the amount normally present varies depending upon sex and age See the What is being tested

An AMH test may be ordered in women when evaluating ovarian function fertility issues especially when considering assisted reproduction procedures such as in vitro fertilization IVF and when a health practitioner wants to determine a woman s likelihood of entering menopause AMH may be ordered when a woman has signs and symptoms of polycystic ovarian syndrome PCOS Some of these include Abnormal uterine bleeding Acanthosis nigricans Acne Absence of menstrual cycle amenorrhea Decreased breast size Enlarged ovaries Excess face and body hair hirsutism involving male hair growth patterns such as hair on the face sideburn area chin upper lip lower abdominal midline chest areola lower back buttock and inner thigh Weight gain obesity with fat distribution in center of the body Skin tags in the armpits or neck Thinning hair with male pattern baldness AMH may be ordered periodically for a woman with an AMH-producing ovarian cancer to monitor the effectiveness of treatment and to monitor for recurrence An AMH test may be ordered when an infant has ambiguous genitalia or when a male child s testicles have not descended properly

Women During a woman s childbearing years a decreased level of AMH may indicate a low number and quality of eggs low ovarian reserve with diminishing fertility resulting in minimal or less responsiveness to IVF treatment It can also indicate that the ovaries are not functioning normally premature ovarian failure A decreasing level and or significant decline in AMH may signal the imminent onset of menopause Negative to low levels of AMH are normal in a female during infancy and after menopause An increased level of AMH is often seen with PCOS but is not diagnostic of this condition Increased AMH may also indicate an increased or even excessive responsiveness to IVF and a need to tailor the procedure accordingly When AMH is used as a tool to monitor an AMH-producing ovarian cancer then a decrease in AMH indicates a response to treatment while an increase may indicate cancer recurrence Infants In a male infant absence or low levels of AMH may indicate a problem with the AMH gene located on chromosome 19 that directs AMH production and may be seen with absent or dysfunctional testicles Lack of male hormones may result in ambiguous genitalia and may cause abnormal internal reproductive structures Normal levels of AMH and androgens in a male infant whose testicles have not descended indicate that they are present and functional but not physically located where they are supposed to be

Some in the medical community are advocating the use of AMH as a more routine test for predicting the end of fertility and the onset of menopause but there is not a consensus on this use It is not considered a diagnostic or stand-alone test but one that supports the diagnosis of one of the conditions mentioned Other female hormones fluctuate with a woman s monthly cycle however AMH is produced by growing follicles at a relatively steady rate It is also not affected by oral contraceptives or pregnancy

For most women the AMH test is not considered necessary unless they are having fertility issues Most women will not need to have this test performed

No testing is not routinely needed It is only indicated when there are questions about a baby s sexual development

No this test requires specialized equipment and must be performed in a laboratory Your blood may need to be sent to a reference laboratory